The mission of the Global Threat Reduction Initiative (GTRI) is to reduce and protect vulnerable nuclear and radiological material located at civilian sites worldwide. GTRI supports the U.S. Department of Energy’s nuclear security goal by preventing terrorists from acquiring nuclear and radiological materials that could be used in weapons of mass destruction or other acts of terrorism. GTRI works towards achieving its mission by converting research reactors and isotope production facilities from the use of highly enriched uranium (HEU) to low enriched uranium (LEU), removing and/or disposing of excess nuclear and radiological materials, and protecting high-priority nuclear and radiological materials from theft. Together, these efforts provide a comprehensive approach to preventing terrorists’ access to nuclear and radiological materials.
GTRI’s Convert program  works with domestic and international civilian research reactors and isotope production facilities to assist them in converting from the use of WMD-usable HEU fuel and targets to LEU fuel and targets. These efforts result in permanent threat reduction by eliminating the need for WMD-usable HEU fuel and targets. Once the need is eliminated, any remaining HEU fresh and spent fuel can be permanently disposed of by GTRI’s Remove Program.
GTRI’s Nuclear and Radiological Material Removal  program removes or disposes of excess WMD-usable nuclear and radiological materials from civilian sites worldwide. The scope of work includes removing Russian-origin nuclear material, U.S.-origin nuclear material, other nuclear material not covered by the Russian and U.S. origin efforts, and removal of excess radiological material worldwide that could be used to make a dirty bomb. These efforts result in permanent threat reduction because WMD-usable material is eliminated.
GTRI’s Nuclear and Radiological Material Protection  program protects at-risk WMD-usable nuclear and radiological materials worldwide from theft and sabotage until a more permanent threat reduction solution can be implemented. These efforts result in threat containment because WMD-usable materials are protected from theft.
Click here  to read highlights of GTRI’s contributions to President Obama’s Four-Year Effort to secure vulnerable nuclear material around the world. See which countries and areas have had HEU or plutonium removed and secured by GTRI with this interactive map .